Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024894 | 0.83 | PPARG (0.43) | PPARDPPARASMN1; SMN2PTPN1 | |
| SCHEMBL3278789 | 0.78 | ALDH1A1 (0.33) | PTPN1 | |
| SCHEMBL7776062 | 0.76 | L3MBTL1 (0.39) | SMN1; SMN2 | |
| SCHEMBL324953 | 0.75 | TDP1 (0.49) | PTGDR2TSHR | |
| SCHEMBL159309 | 0.74 | MRGPRX4 (0.43) | PTPN1PTPN2PTPN6 | |
| SCHEMBL2111994 | 0.74 | PPARD (0.68) | PTGDR2PPARDPPARASMN1; SMN2PTPN1 | |
| SCHEMBL17046319 | 0.73 | CYP1A1 (0.38) | PTGDR2 | |
| SCHEMBL15010621 | 0.72 | HTT (0.42) | PPARDPPARASMN1; SMN2TSHR | |
| SCHEMBL21268265 | 0.72 | PTGDR2 (0.38) | PTGDR2PPARDPPARASMN1; SMN2 | |
| SCHEMBL9025106 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398179-B1 | Rhodanine derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO (JP) | 1996-01-17 | — | — | EP | disclosed |
| US-5116855-A | Aldose reductase inhibitors; antidiabetic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0398179-A1 | Rhodanine derivatives and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |