Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acreozast SCHEMBL6454819 | 0.91 | GPR35 (0.59) | GPR35USP2HPGDSMN1; SMN2CHEK1 | |
| SCHEMBL9234299 | 0.87 | GPR35 (0.49) | GPR35HPGDSMN1; SMN2ALDH1A1TRPM4 | |
| SCHEMBL10335283 | 0.86 | GPR35 (0.54) | GPR35USP2HPGDSMN1; SMN2CHEK1 | |
| SCHEMBL9234654 | 0.81 | GPR35 (0.51) | GPR35ALDH1A1TRPM4KDM4E | |
| SCHEMBL9495446 | 0.78 | GPR35 (0.60) | GPR35USP2HPGDALDH1A1TRPM4 | |
| SCHEMBL9495180 | 0.77 | GPR35 (0.58) | GPR35HPGDSMN1; SMN2ALDH1A1TRPM4 | |
| SCHEMBL9495162 | 0.75 | GPR35 (0.63) | GPR35HPGDALDH1A1HSD17B10TRPM4 | |
| SCHEMBL28582660 | 0.74 | GPR35 (0.79) | GPR35ALDH1A1KDM4E | |
| SCHEMBL10339385 | 0.73 | GPR35 (0.53) | GPR35USP2HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL15413580 | 0.72 | GPR35 (0.45) | GPR35USP2HPGDSMN1; SMN2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2311450-A | — | — | None | — | — | JP | disclosed |
| JP-8003036-A | — | — | None | — | — | JP | disclosed |
| JP-H083036-A | SUPPRESSANT AND ANTIINFLAMMATORY AGENT FOR ACIDOCYTE INFILTRATION | TOYOBO CO LTD | 1996-01-09 | — | — | JP | disclosed |
| EP-0687468-A2 | Pharmaceutical composition for suppressing infiltration of eosinophils | Toyo Boseki Kabushiki Kaisha (JP) | 1995-12-20 | — | — | EP | disclosed |
| JP-H02311450-A | NOVEL BENZONITRILE DERIVATIVE | TOYOBO CO LTD | 1990-12-27 | — | — | JP | disclosed |