Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acreozast SCHEMBL6454819 | 0.86 | GPR35 (0.59) | GPR35GAATRPM4ALDH1A1HPGD | |
| SCHEMBL9495162 | 0.83 | GPR35 (0.63) | GPR35POLBKMT2AMEN1TRPM4 | |
| SCHEMBL9495180 | 0.83 | GPR35 (0.58) | GPR35KMT2AGAATRPM4ALDH1A1 | |
| SCHEMBL10335283 | 0.82 | GPR35 (0.54) | GPR35GAAALDH1A1LMNAHPGD | |
| SCHEMBL10339385 | 0.78 | GPR35 (0.53) | GPR35POLBKMT2AMEN1GAA | |
| SCHEMBL9024019 | 0.78 | GPR35 (0.50) | GPR35TRPM4ALDH1A1HPGDUSP2 | |
| SCHEMBL6439833 | 0.76 | GPR35 (0.63) | GPR35POLBKMT2AMEN1TRPM4 | |
| Lodoxamide Ethyl SCHEMBL667976 | 0.75 | GPR35 (1.00) | GPR35KMT2AGAAALDH1A1L3MBTL1 | |
| SCHEMBL9234299 | 0.75 | GPR35 (0.49) | GPR35KMT2AGAATRPM4ALDH1A1 | |
| SCHEMBL11810185 | 0.71 | GPR35 (0.76) | GPR35GAAALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315112-B1 | NOVEL AMIDE COMPOUNDS | Toyo Boseki Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4912135-A | Benzene ring with amido substitutions in position 1 and 3 | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0315112-A2 | Novel amide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1989-05-10 | — | — | EP | disclosed |