Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9495180 | 0.85 | GPR35 (0.58) | GPR35ALDH1A1HPGDCYP2C19TRPM4 | |
| SCHEMBL9495446 | 0.83 | GPR35 (0.60) | GPR35ALDH1A1MAPTHPGDPOLB | |
| Acreozast SCHEMBL6454819 | 0.83 | GPR35 (0.59) | GPR35ALDH1A1HPGDHSD17B10TRPM4 | |
| SCHEMBL10339385 | 0.81 | GPR35 (0.53) | GPR35ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL10335283 | 0.79 | GPR35 (0.54) | GPR35ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6439833 | 0.79 | GPR35 (0.63) | GPR35ALDH1A1MAPTKDM4EPOLB | |
| Lodoxamide Ethyl SCHEMBL667976 | 0.77 | GPR35 (1.00) | GPR35ALDH1A1MAPTRAB9AKMT2A | |
| SCHEMBL9234299 | 0.77 | GPR35 (0.49) | GPR35ALDH1A1MAPTHPGDTRPM4 | |
| SCHEMBL9024019 | 0.75 | GPR35 (0.50) | GPR35ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL6002909 | 0.71 | HPGD (0.69) | ALDH1A1MAPTHPGDKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315112-B1 | NOVEL AMIDE COMPOUNDS | Toyo Boseki Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4912135-A | Benzene ring with amido substitutions in position 1 and 3 | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-03-27 | — | — | US | disclosed |
| EP-0315112-A2 | Novel amide compounds | Toyo Boseki Kabushiki Kaisha (JP) | 1989-05-10 | — | — | EP | disclosed |