Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538121 | 0.79 | NAMPT (0.49) | C3AR1MAPTHTTNAMPTALDH1A1 | |
| SCHEMBL4489396 | 0.73 | NAMPT (0.54) | C3AR1MAPTHTTNAMPTALDH1A1 | |
| SCHEMBL8538118 | 0.73 | NAMPT (0.52) | MAPTHTTNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8538119 | 0.73 | NAMPT (0.52) | MAPTHTTNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24636716 | 0.70 | MAPT (0.60) | C3AR1MAPTHTTNAMPTALDH1A1 | |
| SCHEMBL11856687 | 0.69 | GAA (0.53) | MAPTHTTNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9024271 | 0.69 | NAMPT (0.48) | MAPTHTTNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9024281 | 0.69 | NAMPT (0.48) | MAPTHTTNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11295721 | 0.68 | MAPT (0.51) | MAPTHTTNAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10881254 | 0.68 | SMN1; SMN2 (0.44) | MAPTHTTNAMPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-A1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | Pfizer Limited (GB) | 1996-06-12 | — | — | EP | disclosed |