Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023944 | 0.88 | KDM4E (0.46) | KMT2AKDM4ELMNASMARCA2MEN1 | |
| SCHEMBL9024437 | 0.82 | NQO2 (0.37) | HTTMAPTMITFNQO1 | |
| SCHEMBL9023958 | 0.81 | TOP2A (0.42) | KMT2AKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL9023868 | 0.81 | NQO2 (0.38) | KMT2ASMARCA2MEN1ALDH1A1HPGD | |
| SCHEMBL9023814 | 0.81 | NQO2 (0.36) | HTTMAPTMITFNQO1 | |
| SCHEMBL9024018 | 0.80 | NQO2 (0.38) | KMT2AKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL9023931 | 0.80 | NQO2 (0.47) | SMARCA2MITFNQO1RAD52 | |
| SCHEMBL8542132 | 0.79 | KMT2A (0.35) | KMT2AKDM4ELMNASMARCA2MEN1 | |
| SCHEMBL9023862 | 0.78 | NQO2 (0.36) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9025305 | 0.78 | NQO2 (0.36) | NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | claimed |
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |