Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | GCGR | P47871 | 4/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024739 | 0.75 | NR4A2 (0.34) | GAAPTGS2GCGR | |
| SCHEMBL9025290 | 0.72 | PTGS2 (0.33) | GAAPTGS2GCGR | |
| SCHEMBL10397582 | 0.70 | GCGR (0.40) | PTGS2GCGR | |
| SCHEMBL9083836 | 0.69 | GCGR (0.33) | GCGR | |
| SCHEMBL9083842 | 0.69 | GCGR (0.33) | GCGR | |
| SCHEMBL9024300 | 0.69 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL9410843 | 0.68 | GCGR (0.32) | GCGR | |
| SCHEMBL9410841 | 0.68 | GCGR (0.32) | GCGR | |
| SCHEMBL8855189 | 0.67 | ALDH1A1 (0.34) | GCGR | |
| SCHEMBL9085590 | 0.67 | GCGR (0.31) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0464845-A1 | Pyrrole derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |