Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 3/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024445 | 0.75 | GAA (0.35) | GAAPTGS2GCGR | |
| SCHEMBL9518155 | 0.72 | HMGCR (0.53) | KDM4EALDH1A1GAASMN1; SMN2NR3C1 | |
| SCHEMBL9518598 | 0.66 | HMGCR (0.56) | — | |
| SCHEMBL10397582 | 0.66 | GCGR (0.40) | PTGS2GCGR | |
| SCHEMBL2574887 | 0.64 | HMGCR (0.40) | ALDH1A1 | |
| SCHEMBL9087114 | 0.64 | LMNA (0.35) | ALDH1A1GAAGCGR | |
| SCHEMBL9087121 | 0.64 | LMNA (0.35) | ALDH1A1GAAGCGR | |
| SCHEMBL9410841 | 0.63 | GCGR (0.32) | GCGR | |
| SCHEMBL9410843 | 0.63 | GCGR (0.32) | GCGR | |
| SCHEMBL9025173 | 0.63 | PRKCZ (0.52) | KDM4EALDH1A1GAASMN1; SMN2GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0464845-A1 | Pyrrole derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1992-01-08 | — | — | EP | disclosed |