Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460239 | 0.84 | ABCB1 (0.53) | ABCB1ALDH1A1MAPTHPGDSLC15A1 | |
| SCHEMBL18925982 | 0.84 | ABCB1 (0.50) | ABCB1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL20426017 | 0.83 | ABCB1 (0.52) | ABCB1ALDH1A1MAPTHPGDSLC15A1 | |
| SCHEMBL30278712 | 0.82 | ABCB1 (0.51) | ABCB1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL13244660 | 0.82 | ABCB1 (0.51) | ABCB1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8276259 | 0.81 | ABCB1 (0.56) | ABCB1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL13489694 | 0.81 | ABCB1 (0.56) | ABCB1ALDH1A1MAPTHPGDSLC15A1 | |
| SCHEMBL5149951 | 0.80 | ABCB1 (0.58) | ABCB1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL14977836 | 0.79 | SIGMAR1 (0.44) | ABCB1ALDH1A1SLC15A1SIGMAR1CYP2C19 | |
| SCHEMBL13373979 | 0.79 | L3MBTL1 (0.51) | ABCB1ALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |