Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024600 | 1.00 | HMGCR (0.43) | HMGCRPKMGPR183KMT2A | |
| SCHEMBL9025064 | 0.82 | HMGCR (0.57) | HMGCR | |
| SCHEMBL9025069 | 0.82 | HMGCR (0.57) | HMGCR | |
| SCHEMBL9024104 | 0.76 | PKM (0.39) | HMGCRPKMGPR183KMT2A | |
| SCHEMBL9024101 | 0.76 | PKM (0.39) | HMGCRPKMGPR183KMT2A | |
| SCHEMBL9024469 | 0.74 | PKM (0.38) | HMGCRPKMGPR183KMT2A | |
| SCHEMBL9518302 | 0.73 | HMGCR (0.66) | HMGCR | |
| SCHEMBL9518920 | 0.73 | HMGCR (0.67) | HMGCR | |
| SCHEMBL10398329 | 0.71 | HMGCR (0.54) | HMGCRKMT2A | |
| SCHEMBL9521396 | 0.69 | HMGCR (0.68) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464845-B1 | Pyrrole derivatives | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5128366-A | Enzyme inhibitors, anticholesterol | SHINOGI & CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |