Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9023772 | 0.99 | ITGB3 (0.59) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| SCHEMBL9023851 | 0.88 | SMN1; SMN2 (0.51) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| SCHEMBL9023933 | 0.84 | SMN1; SMN2 (0.53) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| SCHEMBL9023588 | 0.83 | DPP7 (0.67) | SMN1; SMN2DPP7 | |
| Hydrochloric Acid SCHEMBL9024246 | 0.83 | SMN1; SMN2 (0.52) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| Hydrochloric Acid SCHEMBL9024564 | 0.83 | SMN1; SMN2 (0.50) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| Hydrochloric Acid SCHEMBL9023738 | 0.82 | SMN1; SMN2 (0.43) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| SCHEMBL9024346 | 0.81 | SMN1; SMN2 (0.42) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 | |
| SCHEMBL8837987 | 0.81 | ITGB3 (0.63) | ITGB3ITGA2BHTR1AHTR7 | |
| SCHEMBL9023864 | 0.79 | SMN1; SMN2 (0.40) | ITGB3ITGA2BSMN1; SMN2CYP46A1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718287-A2 | Piperazine derivatives, medicaments containing them, their use, and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1996-06-26 | — | — | EP | claimed |
| EP-0718287-A2 | Piperazine derivatives, medicaments containing them, their use, and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1996-06-26 | — | — | EP | disclosed |