Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.65 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024669 | 0.83 | ITGB3 (0.60) | DPP7SMN1; SMN2 | |
| SCHEMBL23744068 | 0.83 | CHRM4 (0.72) | DPP7SIGMAR1CHRM4CHRM2CCR3 | |
| Hydrochloric Acid SCHEMBL9023772 | 0.82 | ITGB3 (0.59) | DPP7SMN1; SMN2 | |
| SCHEMBL518042 | 0.82 | PRKAA2 (0.90) | PRKAA2 | |
| SCHEMBL23744552 | 0.81 | CHRM4 (0.75) | DPP7CHRM4CHRM2 | |
| SCHEMBL7361343 | 0.80 | POLB (0.59) | DPP7SIGMAR1PRKAA2SMN1; SMN2CHRM4 | |
| SCHEMBL8838013 | 0.80 | SMN1; SMN2 (0.52) | DPP7SIGMAR1SMN1; SMN2CHRM4CHRM2 | |
| SCHEMBL4985269 | 0.79 | SIGMAR1 (0.57) | DPP7SIGMAR1SMN1; SMN2CHRM2CCR3 | |
| SCHEMBL10284376 | 0.79 | PRKAA2 (0.72) | PRKAA2 | |
| SCHEMBL16026613 | 0.78 | DPP7 (0.81) | DPP7SIGMAR1SMN1; SMN2CCR3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718287-A2 | Piperazine derivatives, medicaments containing them, their use, and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1996-06-26 | — | — | EP | disclosed |