Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7296632 | 0.98 | L3MBTL1 (0.41) | L3MBTL1MAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL2875718 | 0.82 | ADRB1 (0.47) | — | |
| SCHEMBL11377242 | 0.75 | HRH1 (0.48) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29353220 | 0.74 | ALDH1A1 (0.41) | L3MBTL1MAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL3436701 | 0.71 | GAA (0.43) | MAPK1HSD17B10MAPTALDH1A1MEN1 | |
| SCHEMBL11818363 | 0.68 | L3MBTL1 (0.36) | L3MBTL1MAPK1HSD17B10MAPTALDH1A1 | |
| SCHEMBL3662718 | 0.67 | ALDH1A1 (0.44) | L3MBTL1MAPK1MAPTALDH1A1MEN1 | |
| SCHEMBL11126858 | 0.66 | PDE4A (0.43) | MAPTALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11105316 | 0.66 | MAPK10 (0.45) | MAPTALDH1A1KDM4ESMN1; SMN2PKM | |
| SCHEMBL14886148 | 0.65 | MAPK8 (0.38) | L3MBTL1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |