Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024437 | 0.78 | NQO2 (0.37) | MAPTHTTIDO1 | |
| SCHEMBL10517310 | 0.77 | NQO2 (0.37) | MAPTHTTIDO1 | |
| SCHEMBL9024018 | 0.76 | NQO2 (0.38) | MAPTHTTIDO1KDM4EMEN1 | |
| SCHEMBL9024559 | 0.75 | MAPT (0.39) | MAPTHTTMEN1KMT2AG6PD | |
| SCHEMBL9024634 | 0.75 | MAPT (0.32) | MAPTHTT | |
| SCHEMBL9023814 | 0.74 | NQO2 (0.36) | MAPTHTTIDO1 | |
| SCHEMBL9036810 | 0.74 | NQO2 (0.36) | IDO1 | |
| SCHEMBL9023868 | 0.72 | NQO2 (0.38) | IDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL9024632 | 0.72 | NQO1 (0.35) | — | |
| SCHEMBL9023942 | 0.72 | NQO1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |