Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023982 | 0.91 | MAPT (0.36) | MAPTHTTG6PD | |
| SCHEMBL9023550 | 0.87 | G6PD (0.46) | MAPTHTTG6PDRECQLMEN1 | |
| SCHEMBL9023672 | 0.79 | G6PD (0.38) | MAPTHTTG6PD | |
| SCHEMBL9023606 | 0.77 | ALDH1A1 (0.34) | MAPTHTTRECQLMEN1LMNA | |
| SCHEMBL9024241 | 0.76 | MAPT (0.32) | MAPTHTT | |
| SCHEMBL9025033 | 0.75 | MAPT (0.35) | MAPTHTTG6PDMEN1KMT2A | |
| SCHEMBL9024634 | 0.75 | MAPT (0.32) | MAPTHTT | |
| SCHEMBL9024132 | 0.74 | ALDH1A1 (0.33) | MAPTHTTRECQLMEN1KMT2A | |
| SCHEMBL8545260 | 0.73 | MAPT (0.41) | MAPTHTTRECQLMEN1LMNA | |
| SCHEMBL9023936 | 0.73 | NQO2 (0.34) | MAPTHTTG6PDCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347749-B1 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO KK (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |