Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834048 | 1.00 | ECE1 (0.38) | ECE1CHRM1CYP19A1SIGMAR1FAAH | |
| SCHEMBL8832957 | 0.87 | ECE1 (0.36) | ECE1CHRM1CYP19A1SIGMAR1FAAH | |
| SCHEMBL9033190 | 0.87 | ECE1 (0.36) | ECE1CHRM1CYP19A1SIGMAR1FAAH | |
| SCHEMBL9027979 | 0.85 | FAAH (0.33) | CHRM1CYP19A1SIGMAR1FAAHMGLL | |
| SCHEMBL9213699 | 0.85 | ECE1 (0.36) | ECE1CHRM1CYP19A1SIGMAR1FAAH | |
| SCHEMBL8833096 | 0.85 | ECE1 (0.36) | ECE1CHRM1CYP19A1SIGMAR1FAAH | |
| SCHEMBL9025504 | 0.85 | FAAH (0.33) | CHRM1CYP19A1SIGMAR1FAAHMGLL | |
| SCHEMBL8832778 | 0.84 | ECE1 (0.36) | ECE1CHRM1CYP19A1SIGMAR1FAAH | |
| SCHEMBL8833609 | 0.84 | ECE1 (0.38) | ECE1CHRM1CYP19A1FAAHMGLL | |
| SCHEMBL8832597 | 0.83 | ECE1 (0.36) | ECE1CHRM1CYP19A1SIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722447-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995010520-A1 | 3-PYRROLIDINYLTHIO-CARBAPENEM DERIVATIVES AND THEIR ANTIMICROBAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-20 | — | — | WO | disclosed |
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |