Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038615 | 0.86 | ALDH1A1 (0.43) | ALDH1A1ALOX15MAOBMAOASMN1; SMN2 | |
| SCHEMBL9053212 | 0.85 | KEAP1 (0.43) | POLBAPEX1ALDH1A1MAOBMAOA | |
| SCHEMBL3621616 | 0.84 | POLB (0.56) | POLBAPEX1HPGDSMN1; SMN2MAPT | |
| SCHEMBL15757221 | 0.82 | POLB (0.46) | POLBAPEX1MAOBMAOAHPGD | |
| SCHEMBL7931028 | 0.81 | ALDH1A1 (0.46) | POLBAPEX1ALDH1A1ALOX15HPGD | |
| SCHEMBL9793665 | 0.79 | ALDH1A1 (0.45) | POLBAPEX1ALDH1A1ALOX15HPGD | |
| SCHEMBL17071867 | 0.79 | POLB (0.43) | POLBAPEX1MAOBMAOAHPGD | |
| SCHEMBL8183434 | 0.78 | KDM4E (0.42) | POLBAPEX1ALDH1A1ALOX15HPGD | |
| SCHEMBL19433388 | 0.78 | POLB (0.43) | POLBAPEX1ALDH1A1MAOBMAOA | |
| SCHEMBL2630704 | 0.78 | POLB (0.46) | POLBAPEX1MAOBMAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8259521-A | — | — | None | — | — | JP | disclosed |
| JP-H08259521-A | SUBSTITUTED BENZOYL CHLORIDE DERIVATIVE AND ITS PRODUCTION | CENTRAL GLASS CO LTD | 1996-10-08 | — | — | JP | disclosed |