Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.43 |
| ▸ | S100A10 | P60903 | 1/20 | 0.43 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713109 | 0.85 | PLA2G2A (0.48) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL15286842 | 0.85 | RXRA (0.51) | RXRARXRBRXRGTP53HTT | |
| SCHEMBL29787364 | 0.84 | RXRA (0.47) | RXRARXRBRXRGTP53HTT | |
| SCHEMBL8848536 | 0.84 | RXRA (0.47) | RXRARXRBRXRGTP53HTT | |
| SCHEMBL5291219 | 0.83 | HTT (0.68) | RXRARXRBRXRGTP53HTT | |
| SCHEMBL8948906 | 0.83 | RXRA (0.51) | RXRARXRBRXRGTP53HTT | |
| SCHEMBL7965281 | 0.82 | TP53 (0.54) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL8205297 | 0.81 | HIF1A (0.50) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL7779845 | 0.81 | HIF1A (0.50) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL9442052 | 0.81 | L3MBTL1 (0.52) | KMT2ARXRARXRBRXRGTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493711-B1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF AG (DE) | 1996-09-25 | — | — | EP | disclosed |
| EP-0554767-B1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF AG (DE) | 1996-06-19 | — | — | EP | disclosed |
| US-5354883-A | Forming stereospecific in a acid catalysts, salt formation with a base, methylating in an organic diluent | BASF AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| EP-0554767-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |