Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025877 | 0.93 | CHRNA7 (0.40) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL7128063 | 0.88 | CHRNA7 (0.43) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL7127186 | 0.81 | CHRNA7 (0.41) | CHRNA7MEN1KMT2ATDP1CHRNB2 | |
| SCHEMBL9025632 | 0.77 | PSEN1 (0.43) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNB4 | |
| SCHEMBL9025229 | 0.77 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7664585 | 0.70 | SMN1; SMN2 (0.52) | CHRNA7CHRNB2CHRNA4ALDH1A1CHRNA3 | |
| SCHEMBL14628597 | 0.69 | CHRNA3 (0.55) | CHRNA7CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL7128401 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL7128400 | 0.69 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL3256237 | 0.69 | CHRNB2 (0.39) | CHRNA7MEN1KMT2ATDP1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693066-A1 | NOVEL 2-NITROMETHYLIDENE/2-CYANIMINO/2-NITRO-IMINO-PYRROLIDINES AND PIPERIDINES, INTERMEDIATES, AND THEIR USE AS PESTICIDES | Novartis AG (CH) | 1996-01-24 | — | — | EP | disclosed |