Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026138 | 0.82 | RAB9A (0.49) | GRM1HTTCYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL9026522 | 0.80 | FLT3 (0.40) | CYP3A4CYP17A1CYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL15839017 | 0.76 | CYP11B2 (0.49) | GRM1CYP2A6CYP2E1CYP3A4CYP11B2 | |
| SCHEMBL9026635 | 0.75 | CYP2A6 (0.44) | GRM1CYP2A6CYP2E1CYP3A4CYP11B2 | |
| SCHEMBL23130664 | 0.74 | ALDH1A1 (0.50) | CYP3A4HTTCYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL2691288 | 0.74 | NAMPT (0.46) | GRM1CYP11B2NAMPTHTTCYP1A2 | |
| SCHEMBL2691172 | 0.73 | CYP2A6 (0.49) | GRM1CYP2A6CYP2E1CYP3A4CYP11B2 | |
| SCHEMBL2689168 | 0.72 | CYP2A6 (0.45) | GRM1CYP2A6CYP2E1CYP3A4CYP11B2 | |
| SCHEMBL2689254 | 0.72 | SMN1; SMN2 (0.45) | GRM1CYP2A6CYP2E1CYP3A4ALDH1A1 | |
| SCHEMBL15839015 | 0.72 | CYP11B2 (0.58) | GRM1CYP2A6CYP2E1CYP3A4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220028-A | Halogeno-4-methylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-15 | — | — | US | claimed |
| EP-0366329-B1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL IND LTD (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5220028-A | Halogeno-4-methylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0366329-A1 | Halogeno-4-methylpyrazoles and process for preparing the same | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-05-02 | — | — | EP | disclosed |