Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 2/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025939 | 0.81 | L3MBTL1 (0.55) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL30762034 | 0.80 | L3MBTL1 (0.56) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL3132751 | 0.77 | L3MBTL1 (0.61) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL31126240 | 0.75 | L3MBTL1 (0.63) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL273000 | 0.75 | L3MBTL1 (0.63) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL4109142 | 0.74 | L3MBTL1 (0.66) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL22651784 | 0.74 | L3MBTL1 (0.70) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL30721514 | 0.74 | L3MBTL1 (0.66) | L3MBTL1PDE10AEPHX1ADAM17HTR6 | |
| SCHEMBL25907970 | 0.74 | AAK1 (0.50) | AAK1 | |
| SCHEMBL4892277 | 0.73 | L3MBTL1 (0.65) | L3MBTL1PDE10AEPHX1ADAM17HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411150-B1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMA CO LTD (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5238938-A | Nephrosis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0411150-A1 | INDOLE DERIVATIVES, PREPARATION THEREOF, AND DRUG FOR PREVENTING AND TREATING NEPHRITIS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |