Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132751 | 0.88 | L3MBTL1 (0.61) | L3MBTL1EPHX1NR1H2PDE10AHTR6 | |
| SCHEMBL1520892 | 0.85 | L3MBTL1 (0.70) | L3MBTL1EPHX1PDE10AHTR6ADAM17 | |
| SCHEMBL10088115 | 0.85 | L3MBTL1 (0.74) | L3MBTL1EPHX1PDE10AHTR6ADAM17 | |
| SCHEMBL29353520 | 0.83 | HTR6 (0.51) | L3MBTL1EPHX1NR1H2HTR6ACHE | |
| SCHEMBL15777186 | 0.83 | L3MBTL1 (0.45) | L3MBTL1EPHX1NR1H2PDE10AHTR6 | |
| SCHEMBL1241271 | 0.83 | L3MBTL1 (0.45) | L3MBTL1EPHX1NR1H2PDE10AHTR6 | |
| SCHEMBL19273398 | 0.83 | L3MBTL1 (0.45) | L3MBTL1EPHX1NR1H2PDE10AHTR6 | |
| SCHEMBL29352824 | 0.83 | L3MBTL1 (0.45) | L3MBTL1EPHX1NR1H2PDE10AHTR6 | |
| SCHEMBL15776738 | 0.83 | HTR6 (0.51) | L3MBTL1EPHX1NR1H2HTR6ACHE | |
| SCHEMBL15776173 | 0.83 | HTR6 (0.51) | L3MBTL1EPHX1NR1H2HTR6NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851054-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | BIOKINESIS (FR) | 2020-12-01 | — | — | US | disclosed |
| US-20190169124-A1 | NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER, VIRAL INFECTIONS AND LUNG DISEASES | DIACCURATE (FR) | 2019-06-06 | — | — | US | disclosed |
| US-10189782-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | BIOKINESIS (FR) | 2019-01-29 | — | — | US | disclosed |
| US-10155259-B2 | FSH receptor antagonists | MERCK SHARP & DOHME B.V. (NL) | 2018-12-18 | — | — | US | disclosed |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ATXCO, INC. | 2018-06-14 | — | — | US | disclosed |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ATXCO, INC. | 2018-06-14 | — | — | US | disclosed |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ATXCO, INC. | 2018-06-14 | — | — | US | disclosed |
| US-9926318-B2 | Tetracyclic autotaxin inhibitors | PHARMAKEA, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| US-9926318-B2 | Tetracyclic autotaxin inhibitors | PHARMAKEA, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| US-9926318-B2 | Tetracyclic autotaxin inhibitors | PHARMAKEA, INC. (US) | 2018-03-27 | — | — | US | disclosed |
| US-6831175-B2 | Such as N,N-dimethyl-N-(2-((5-((E)-2-pyridin-4-ylvinyl) pyridin-3-yl)oxy)ethyl)amine | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | disclosed |
| US-20040235839-A1 | Beta-carbolines useful for treating inflammatory disease | MILLENNIUM PHARMACEUTICALS, INC. | 2004-11-25 | — | — | US | disclosed |
| WO-2004092167-A1 | BETA-CARBOLINES USEFUL FOR TREATING INFLAMMATORY DISEASE | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| EP-1463505-A2 | 3-(PHENYL-ALKOXY)-5-(PHENYL)-PYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Abbott Laboratories (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20040097574-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-05-20 | — | — | US | disclosed |
| WO-2004019935-A1 | -3 (SULFONAMIDOETHYL) -INDOLE DERIVATIES FOR USE AS GLUCOCORTICOID MIMETICS IN THE TREATMENT OF INFLAMMATORY, ALLERGIC AND PROLIFERATIVE DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-03-11 | — | — | WO | disclosed |
| US-20040023947-A1 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents | X-CEPTOR THERAPEUTICS INC. | 2004-02-05 | — | — | US | disclosed |
| US-20030199511-A1 | Kinase inhibitors | ABBVIE INC. | 2003-10-23 | — | — | US | disclosed |
| US-20030187026-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-10-02 | — | — | US | disclosed |
| WO-2003051366-A2 | 3-(PHENYL-ALKOXY)-5-(PHENYL)-PYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | ABBOTT LABORATORIES (US) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187026-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | L3MBTL1 2447/4885EPHX1 3039/4885NR1H2 3482/4885 |
| US-20180162859-A1 | TETRACYCLIC AUTOTAXIN INHIBITORS | ENPP2, SERPINB1, UACA | L3MBTL1 2352/4885EPHX1 2730/4885NR1H2 3175/4885 |
| US-20040023947-A1 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents | HTR5A, MTNR1A, PTGDR | L3MBTL1 4876/4885EPHX1 1209/4885NR1H2 474/4885 |
| US-20040235839-A1 | Beta-carbolines useful for treating inflammatory disease | NFKBIA, IRAK2, IRAK1 | L3MBTL1 1137/4885EPHX1 3514/4885NR1H2 246/4885 |
| US-20030199511-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | L3MBTL1 2447/4885EPHX1 3039/4885NR1H2 3482/4885 |
| US-20190169124-A1 | NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER, VIRAL INFECTIONS AND LUNG DISEASES | IDO2, IDO1, ING2 | L3MBTL1 1926/4885EPHX1 2707/4885NR1H2 1078/4885 |
| US-20040097574-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, NR3C2, MC2R | L3MBTL1 3888/4885EPHX1 1191/4885NR1H2 88/4885 |
| US-10189782-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | IDO2, IDO1, ING2 | L3MBTL1 1548/4885EPHX1 2419/4885NR1H2 662/4885 |
| US-10155259-B2 | FSH receptor antagonists | FSHR, GNRHR, LHCGR | L3MBTL1 4844/4885EPHX1 3649/4885NR1H2 142/4885 |
| US-10851054-B2 | Derivatives of indole for the treatment of cancer, viral infections and lung diseases | IDO2, IDO1, ING2 | L3MBTL1 1548/4885EPHX1 2419/4885NR1H2 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.