Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026272 | 0.94 | KMT2A (0.56) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL4544899 | 0.82 | LMNA (0.61) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL27947134 | 0.82 | LMNA (0.61) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL9025302 | 0.81 | ELANE (0.50) | KMT2AALDH1A1SMN1; SMN2POLBSLC6A3 | |
| SCHEMBL9025308 | 0.77 | ALDH1A1 (0.47) | KMT2AALDH1A1SMN1; SMN2POLBSLC6A3 | |
| SCHEMBL12266961 | 0.76 | MEN1 (0.52) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL30878614 | 0.75 | LMNA (0.51) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL29418226 | 0.74 | LMNA (0.74) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL7922562 | 0.74 | LMNA (0.74) | LMNAKMT2AALDH1A1MEN1PPARG | |
| SCHEMBL819332 | 0.74 | LMNA (0.74) | LMNAKMT2AALDH1A1MEN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719774-A1 | A method for production of dibenzoxazolyl thiophenes | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5310940-A | Sulfiding, cyclization | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5221749-A | Reacting a thiophene,2,5-dicarboxylic acid diester with a 2-aminophenol in the presence of an acid catalyst | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-5093504-A | PRODUCTION OF THIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS, TETRAHYDROTHIOPHENE-2,5-DICARBOXYLIC ACID DIESTERS AND DIBENZOXAZOLYLTHIOPHENES | SUMITOMO SEIKA CHEMICALS, CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0387725-A2 | Production of thiophene-2,5-dicarboxylic acid diesters and tetrahydrothiophene-2,5-dicarboxylic acid diesters | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |