Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | EBP | Q15125 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220066 | 0.90 | MEN1 (0.42) | — | |
| SCHEMBL9026945 | 0.83 | HTR1A (0.52) | — | |
| SCHEMBL9026126 | 0.83 | HRH3 (0.48) | HRH3 | |
| SCHEMBL9026614 | 0.79 | SIGMAR1 (0.43) | SIGMAR1EBPTMEM97LMNANPSR1 | |
| SCHEMBL9025857 | 0.78 | SIGMAR1 (0.40) | SIGMAR1EBPTMEM97LMNANPSR1 | |
| SCHEMBL9031394 | 0.78 | SIGMAR1 (0.40) | SIGMAR1EBPTMEM97LMNANPSR1 | |
| SCHEMBL9029451 | 0.78 | SIGMAR1 (0.40) | SIGMAR1EBPTMEM97LMNANPSR1 | |
| SCHEMBL9026266 | 0.78 | SIGMAR1 (0.40) | SIGMAR1HRH3EBPTMEM97LMNA | |
| SCHEMBL9030858 | 0.78 | KDM4E (0.39) | LMNA | |
| SCHEMBL9025554 | 0.77 | MAPK14 (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |