Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025502 | 0.86 | PDE7A (0.37) | KDM4EL3MBTL1MAPK1ALDH1A1LMNA | |
| SCHEMBL9025304 | 0.85 | KDM4E (0.37) | KDM4EL3MBTL1PTGDRMAPK1ALDH1A1 | |
| SCHEMBL9220066 | 0.83 | MEN1 (0.42) | KMT2AMEN1 | |
| SCHEMBL9025554 | 0.81 | MAPK14 (0.39) | KDM4EL3MBTL1MAPK1ALDH1A1LMNA | |
| SCHEMBL9030860 | 0.78 | KDM4E (0.39) | KDM4EL3MBTL1PTGDRMAPK1ALDH1A1 | |
| SCHEMBL9026284 | 0.78 | SIGMAR1 (0.47) | LMNA | |
| SCHEMBL9026126 | 0.75 | HRH3 (0.48) | KDM4EL3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL9025816 | 0.73 | KDM4E (0.35) | KDM4EL3MBTL1MAPK1ALDH1A1LMNA | |
| SCHEMBL9032013 | 0.72 | MAPT (0.37) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL9025513 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |