Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025981 | 0.84 | MAPK1 (0.36) | MAPK1ALDH1A1SLC9A1HTTMAPT | |
| SCHEMBL9026839 | 0.81 | MAPK1 (0.40) | MAPK1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9025534 | 0.79 | MAPK1 (0.40) | MAPK1ALDH1A1SLC9A1MEN1KMT2A | |
| SCHEMBL9026568 | 0.77 | MAPK1 (0.39) | MAPK1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9026849 | 0.77 | MAPK1 (0.37) | MAPK1SLC9A1MEN1KMT2AMAPT | |
| SCHEMBL9025289 | 0.76 | MAPK1 (0.38) | MAPK1ALDH1A1SLC9A1HTTMEN1 | |
| SCHEMBL9218807 | 0.76 | MAPK1 (0.39) | MAPK1ALDH1A1SLC9A1MEN1KMT2A | |
| SCHEMBL9026532 | 0.75 | AGXT (0.38) | SLC9A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9026477 | 0.75 | SLC9A1 (0.36) | MAPK1ALDH1A1SLC9A1HTTTDP1 | |
| SCHEMBL9025839 | 0.74 | PTGDR2 (0.39) | ALDH1A1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |