Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025996 | 0.84 | SLC9A1 (0.34) | SLC9A1HTTHTR3EHTR3BHTR3A | |
| SCHEMBL9026642 | 0.81 | KMT2A (0.39) | SLC9A1HTTHPGDALDH1A1MAPT | |
| SCHEMBL9026470 | 0.80 | HTT (0.35) | SLC9A1HTTALDH1A1HTR3EHTR3B | |
| SCHEMBL9025555 | 0.79 | ADORA2A (0.40) | SLC9A1GAAHPGDALDH1A1HTR3E | |
| SCHEMBL9026585 | 0.76 | MAPT (0.36) | SLC9A1HPGDALDH1A1MAPTMAPK1 | |
| SCHEMBL9025299 | 0.76 | SLC9A1 (0.34) | SLC9A1HTTGAAHPGDALDH1A1 | |
| SCHEMBL9218822 | 0.75 | KMT2A (0.36) | SLC9A1HTTHPGDALDH1A1HTR3E | |
| SCHEMBL9026866 | 0.75 | RXFP1 (0.36) | SLC9A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9026539 | 0.75 | SLC9A1 (0.37) | SLC9A1HTTHPGDALDH1A1ALOX5 | |
| SCHEMBL9026467 | 0.75 | MAPK1 (0.35) | SLC9A1HTTALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |