Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9027812 | 0.81 | — | — | |
| SCHEMBL9027734 | 0.80 | ADRA1D (0.75) | — | |
| Hydrochloric Acid SCHEMBL9027255 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL9026670 | 0.79 | ADRA1D (0.74) | — | |
| Hydrochloric Acid SCHEMBL9025955 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9027618 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL9026749 | 0.75 | — | — | |
| Oxalic Acid SCHEMBL9026931 | 0.75 | DRD2 (0.73) | — | |
| SCHEMBL9028641 | 0.75 | DRD2 (0.59) | — | |
| Oxalic Acid SCHEMBL9026393 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |