Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9027255 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL9025955 | 0.83 | KDM4E (0.65) | DRD2HTR2A | |
| SCHEMBL9027618 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL9026749 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL9028166 | 0.80 | L3MBTL1 (0.56) | DRD2DRD3HTR2ADRD4 | |
| SCHEMBL6933957 | 0.80 | HTR1A (0.70) | DRD2DRD3DRD4 | |
| SCHEMBL9028512 | 0.79 | KDM4E (0.68) | DRD2DRD3HTR2A | |
| Hydrochloric Acid SCHEMBL8828517 | 0.79 | — | — | |
| SCHEMBL5655837 | 0.79 | DRD2 (0.63) | DRD2DRD3HTR2ADRD4 | |
| SCHEMBL6928363 | 0.78 | DRD2 (0.64) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711757-A1 | 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists | F. Hoffmann-La Roche AG (CH) | 1996-05-15 | — | — | EP | disclosed |