Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025551 | 0.82 | KDM4E (0.43) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9278514 | 0.81 | KDM4E (0.39) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9025501 | 0.81 | HPGD (0.50) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9026850 | 0.78 | KDM4E (0.50) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9030873 | 0.77 | DRD2 (0.39) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9216010 | 0.77 | RAB9A (0.42) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9025085 | 0.77 | RAB9A (0.43) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9024885 | 0.77 | KDM4E (0.43) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9026001 | 0.77 | KMT2A (0.42) | TSHRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9026660 | 0.76 | MAPT (0.35) | TSHRKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |