Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107900 | 0.88 | L3MBTL1 (0.59) | TSHRL3MBTL1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL8084575 | 0.86 | MEN1 (0.55) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL8620935 | 0.85 | L3MBTL1 (0.56) | TSHRL3MBTL1HPGDSMN1; SMN2TDP1 | |
| Acetone SCHEMBL7728200 | 0.85 | L3MBTL1 (0.56) | TSHRL3MBTL1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL12923057 | 0.85 | LMNA (0.64) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL11879591 | 0.84 | LMNA (0.75) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL11622858 | 0.84 | PPARG (0.47) | LMNAGAAL3MBTL1HPGDKMT2A | |
| SCHEMBL22570782 | 0.83 | LMNA (0.68) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL3381526 | 0.83 | LMNA (0.62) | LMNAABCC4GAATSHRPTGS1 | |
| SCHEMBL11142957 | 0.82 | L3MBTL1 (0.50) | LMNAGAAHTTL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729464-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0729463-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |