Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026137 | 0.90 | HRH3 (0.43) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL9027015 | 0.77 | HRH3 (0.39) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL9026523 | 0.77 | HTR2A (0.66) | HTR2CALDH1A1KMT2ABCHEHTR2A | |
| SCHEMBL9027173 | 0.76 | HTR1A (0.58) | HTR2BKMT2AMAPTHTR2ADRD2 | |
| SCHEMBL9027033 | 0.75 | HTR2A (0.65) | HTR2CALDH1A1KMT2ABCHEHTR2A | |
| SCHEMBL734498 | 0.74 | HTR2C (0.73) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL736020 | 0.74 | OPRM1 (0.41) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL7951597 | 0.72 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL734234 | 0.72 | OPRL1 (0.43) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL20148244 | 0.71 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |