Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028740 | 0.89 | KDM4E (0.39) | KDM4EKMT2AMEN1GAAHTT | |
| SCHEMBL9028345 | 0.80 | KDM4E (0.42) | KDM4EKMT2AMEN1GAAHTT | |
| SCHEMBL9027155 | 0.78 | MEN1 (0.52) | KDM4EKMT2AMEN1GAAHTT | |
| SCHEMBL8884481 | 0.77 | MEN1 (0.47) | KDM4EKMT2AMEN1GAAHTT | |
| SCHEMBL9028275 | 0.73 | CASP1 (0.39) | KMT2AMEN1GAAHTTLMNA | |
| SCHEMBL9027955 | 0.73 | ALDH1A1 (0.39) | KDM4EKMT2AMEN1GAAHTT | |
| SCHEMBL9027499 | 0.72 | TACR1 (0.44) | SLC6A4SLC6A3 | |
| SCHEMBL9028585 | 0.71 | TACR2 (0.45) | KMT2AMEN1ALDH1A1POLBSLC6A4 | |
| SCHEMBL9027877 | 0.71 | HRH1 (0.40) | SLC6A4SLC6A3 | |
| SCHEMBL8884449 | 0.70 | TACR2 (0.55) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563133-A | NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0714891-A1 | Heterocyclic tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-06-05 | — | — | EP | disclosed |