SCHEMBL90273

SCHEMBL90273

CCCCCN1CCC=N1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 3/20 0.34
GNAO1 P09471 3/20 0.34
GNAI1 P63096 3/20 0.34
TBXAS1 P24557 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MGLL Q99685 2/20 0.32
FAAH O00519 1/20 0.32
TLR8 Q9NR97 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27548581 0.98 GNAI3 (0.37) GNAI3GNAO1GNAI1TBXAS1MEN1
SCHEMBL27465544 0.98 GNAI3 (0.37) GNAI3GNAO1GNAI1TBXAS1MEN1
SCHEMBL7026105 0.94
Methylamine SCHEMBL27909059 0.90 ADORA2A (0.30)
SCHEMBL7023666 0.85
SCHEMBL28276357 0.78
SCHEMBL14134951 0.71
Methylamine SCHEMBL27892054 0.71
SCHEMBL11030624 0.68 GNAI3 (0.32) GNAI3GNAO1GNAI1TBXAS1MEN1
SCHEMBL16667540 0.67 TBXAS1 (0.33) GNAI3GNAO1GNAI1TBXAS1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101429162-A Method for producing 1-phenyl-3,5-di-substituted aryl-2-pyrazoline HUAIYIN TEACHERS COLLEGE (CN) 2009-05-13 CN claimed
EP-0720047-B1 Photographic element containing a stable aryloxypyrazolone coupler and process employing the same EASTMAN KODAK CO (US) 2002-07-03 EP claimed
EP-0720048-B1 Photographic element containing pyrazolone pug releasing coupler and imaging process employing same EASTMAN KODAK CO (US) 2001-10-24 EP claimed
EP-0322691-B1 Process for producing 1-acyl-2-pyrazoline derivatives MITSUI TOATSU CHEMICALS (JP) 1994-06-15 EP claimed
CN-1015177-B Method for producing 1-acyl-2-pyrazoline derivative MITSUI TOATSU CHEMICALS (JP) 1991-12-25 CN claimed
EP-0146411-B1 PHOTOSOLUBILISABLE COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-07-31 EP claimed
US-4895947-A Process for producing 1-acyl-2-pyrazoline derivative MITSUI TOATSU CHEMICALS, INC. (JP) 1990-01-23 US claimed
CN-1033994-A Produce the method for 1-acyl-2-pyrazoline derivative MITSUI TOATSU CHEMICALS (JP) 1989-07-19 CN claimed
EP-0322691-A1 Process for producing 1-acyl-2-pyrazoline derivatives MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-07-05 EP claimed
US-4708925-A PRINTING PLATES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-24 US claimed
EP-0146411-A2 Photosolubilisable compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-26 EP claimed
US-4312855-A FOR IMPROVING DEPOSITION OR RETENTION OF ACTIVE MATERIAL; HAIR CONDITIONERS, DETERGENTS COLGATE-PALMOLIVE COMPANY (US) 1982-01-26 US claimed
US-4250053-A WITH FLUORESCENT COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-02-10 US claimed
EP-2778782-B1 Negative working radiation-sensitive elements KODAK GRAPHIC COMM GMBH (DE) 2015-12-30 EP disclosed
EP-2212747-B1 PHOTOPATTERNABLE DEPOSITION INHIBITOR CONTAINING SILOXANE EASTMAN KODAK CO (US) 2015-07-22 EP disclosed
US-8906490-B2 Multicolor mask EASTMAN KODAK COMPANY (US) 2014-12-09 US disclosed
US-4312855-A FOR IMPROVING DEPOSITION OR RETENTION OF ACTIVE MATERIAL; HAIR CONDITIONERS, DETERGENTS COLGATE-PALMOLIVE COMPANY (US) 1982-01-26 US disclosed
US-4250053-A WITH FLUORESCENT COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-02-10 US disclosed
EP-0011693-A1 N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth CIBA-GEIGY AG (CH) 1980-06-11 EP disclosed
US-RE29554-E Organic photoconductive members comprising dicyanomethylene substituted fluorene sensitizers ADDRESSOGRAPH-MULTIGRAPH CORPORATION (US) 1978-02-28 US disclosed