Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535657 | 0.90 | POLB (0.43) | POLBALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL8538794 | 0.86 | L3MBTL1 (0.46) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL8539172 | 0.86 | ALDH1A1 (0.44) | ALDH1A1HPGDTDP1MAPTGAA | |
| SCHEMBL8534016 | 0.83 | CTSB (0.47) | POLBALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL8534302 | 0.82 | KDM4E (0.46) | ALDH1A1HPGDL3MBTL1MEN1HSP90AA1 | |
| SCHEMBL8534689 | 0.79 | CTSB (0.42) | ALDH1A1HPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL9026701 | 0.76 | ELANE (0.42) | ELANEPOLBEGFRGSTP1GSTM2 | |
| SCHEMBL6954786 | 0.73 | SMN1; SMN2 (0.50) | ELANEPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9025993 | 0.71 | POLB (0.52) | ELANEPOLBGSTP1GSTM2ALDH1A1 | |
| SCHEMBL8537538 | 0.70 | KMT2A (0.42) | ELANEPOLBALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729463-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | claimed |