Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094230 | 0.79 | CYP2A6 (0.50) | TDP1CYP2A6F12PLAUNCF1 | |
| SCHEMBL28006480 | 0.77 | PLAU (0.56) | L3MBTL1TDP1CYP2A6F12PLAU | |
| SCHEMBL12794530 | 0.76 | PLAU (0.47) | L3MBTL1TDP1CYP2A6F12PLAU | |
| SCHEMBL15881921 | 0.75 | HTT (0.59) | L3MBTL1TDP1HTTMAPTTSHR | |
| SCHEMBL7034890 | 0.73 | ALDH1A1 (0.50) | L3MBTL1TDP1CYP2A6F12PLAU | |
| SCHEMBL2607720 | 0.73 | L3MBTL1 (0.50) | L3MBTL1TDP1HTTMAPTMEN1 | |
| SCHEMBL20123201 | 0.72 | CYP2A6 (0.43) | TDP1CYP2A6F12PLAUNCF1 | |
| SCHEMBL29172556 | 0.72 | ALDH1A1 (0.46) | TDP1CYP2A6F12PLAUNCF1 | |
| SCHEMBL28006481 | 0.72 | CYP2A6 (0.50) | L3MBTL1TDP1CYP2A6F12PLAU | |
| SCHEMBL11612248 | 0.72 | CYP2A6 (0.55) | L3MBTL1TDP1CYP2A6F12PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390099-B1 | Polar cephalosporin derivatives and process for their preparation | HOECHST AG (DE) | 1996-06-26 | — | — | EP | claimed |
| CN-1062772-A | The method of making the sieve material of low internal stress reaches the sieve material that makes thus | STORK SCREENS BV (NL) | 1992-07-15 | — | — | CN | claimed |
| JP-2289585-A | — | — | None | — | — | JP | disclosed |
| CN-1038605-C | Method for forming sieve material having low internal stress and sieve material so obtained | STORK SCREENS BV (NL) | 1998-06-03 | — | — | CN | disclosed |
| JP-H02289585-A | POLAR CEPHALOSPORIN DERIVATIVE AND ITS PREPARATION | HOECHST AG | 1990-11-29 | — | — | JP | disclosed |