Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034890 | 0.80 | ALDH1A1 (0.50) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL20123201 | 0.79 | CYP2A6 (0.43) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL29172556 | 0.79 | ALDH1A1 (0.46) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL1094230 | 0.79 | CYP2A6 (0.50) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL28006480 | 0.77 | PLAU (0.56) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL9027635 | 0.76 | L3MBTL1 (0.47) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL11456732 | 0.73 | PLAU (0.44) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL24430064 | 0.73 | L3MBTL1 (0.40) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL28006481 | 0.72 | CYP2A6 (0.50) | PLAUF12NCF1NOS3NOS1 | |
| SCHEMBL11612248 | 0.72 | CYP2A6 (0.55) | PLAUF12NCF1NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180108492-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION | FUJIFILM CORPORATION (JP) | 2018-04-19 | — | — | US | disclosed |
| US-20180108492-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION | FUJIFILM CORPORATION (JP) | 2018-04-19 | — | — | US | disclosed |
| EP-2488544-B1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | UNIV MONASH (AU) | 2015-03-18 | — | — | EP | disclosed |
| US-8748582-B2 | Affinity ligands and methods for protein purification | MONASH UNIVERSITY (AU) | 2014-06-10 | — | — | US | disclosed |
| US-8748582-B2 | Affinity ligands and methods for protein purification | MONASH UNIVERSITY (AU) | 2014-06-10 | — | — | US | disclosed |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY | 2012-10-11 | — | — | US | disclosed |
| WO-2011044637-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MONASH UNIVERSITY (AU) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180108492-A1 | PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND COMPOSITION | SCNN1A, CRY1, NR2E3 | PLAU 4668/4885F12 492/4885NCF1 875/4885 |
| US-20120259094-A1 | AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION | MAX, SPR, CCL2 | PLAU 1718/4885F12 198/4885NCF1 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.