Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.53 |
| ▸ | FPR2 | P25090 | 13/20 | 0.46 |
| ▸ | FPR1 | P21462 | 8/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7418870 | 1.00 | ITGB3 (0.53) | ITGB3ITGA2BFPR2FPR1F10 | |
| SCHEMBL8116032 | 0.96 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1F10 | |
| SCHEMBL8116018 | 0.96 | ITGB3 (0.57) | ITGB3ITGA2BFPR2FPR1F10 | |
| Trifluoroacetic Acid SCHEMBL7422390 | 0.91 | ITGB3 (0.62) | ITGB3ITGA2BFPR2FPR1F10 | |
| SCHEMBL7418876 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1F10 | |
| Trifluoroacetic Acid SCHEMBL7414816 | 0.86 | FPR2 (0.44) | FPR2FPR1 | |
| SCHEMBL8117283 | 0.85 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1F10 | |
| SCHEMBL8117290 | 0.85 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1F10 | |
| Trifluoroacetic Acid SCHEMBL7424525 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BFPR2FPR1F7 | |
| Trifluoroacetic Acid SCHEMBL7411796 | 0.82 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | disclosed |