Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7414816

NN=Cc1ccc(N2CC[C@H](NC(=O)Nc3cccc(CCC(=O)O)c3)C2=O)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 19/20 0.44
FPR1 P21462 10/20 0.44
NPY1R P25929 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8116040 0.96 FPR2 (0.47) FPR2FPR1NPY1R
Trifluoroacetic Acid SCHEMBL7422393 0.92 ITGB3 (0.46) FPR2FPR1NPY1R
SCHEMBL8117293 0.86 ITGB3 (0.50) FPR2FPR1NPY1R
Trifluoroacetic Acid SCHEMBL9027645 0.86 ITGB3 (0.53) FPR2FPR1
Trifluoroacetic Acid SCHEMBL7418870 0.86 ITGB3 (0.53) FPR2FPR1
Trifluoroacetic Acid SCHEMBL7424548 0.83 ITGB3 (0.42) FPR2FPR1
Trifluoroacetic Acid SCHEMBL7411809 0.83 ITGB3 (0.50) FPR2FPR1
SCHEMBL8116032 0.81 ITGB3 (0.57) FPR2FPR1NPY1R
SCHEMBL8116018 0.81 ITGB3 (0.57) FPR2FPR1NPY1R
Trifluoroacetic Acid SCHEMBL7422390 0.79 ITGB3 (0.62) FPR2FPR1NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3034046-B2 2000-04-17 JP claimed
EP-0691953-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-01-17 EP claimed
WO-1994022820-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-10-13 WO claimed
EP-0691953-B1 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS SEARLE & CO (US) 2000-08-02 EP disclosed
EP-0691953-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1996-01-17 EP disclosed
WO-1994022820-A1 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS G.D. SEARLE & CO. (US) 1994-10-13 WO disclosed