Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270855 | 0.87 | EBP (0.69) | EBPSIGMAR1TMEM97ABCB1 | |
| SCHEMBL1965491 | 0.86 | ATM (0.63) | ALDH1A1SMN1; SMN2HTTPOLBATM | |
| SCHEMBL9027195 | 0.84 | SIGMAR1 (0.54) | EBPSIGMAR1TMEM97ALDH1A1HTR1A | |
| SCHEMBL1678220 | 0.82 | KMT2A (0.67) | ALDH1A1SMN1; SMN2HTTPOLBATM | |
| SCHEMBL27337543 | 0.79 | SIGMAR1 (0.64) | EBPSIGMAR1TMEM97 | |
| SCHEMBL3824304 | 0.79 | HTR1A (0.61) | EBPSIGMAR1TMEM97HTR1ASLC6A4 | |
| SCHEMBL27334030 | 0.78 | SIGMAR1 (0.56) | EBPSIGMAR1TMEM97ALDH1A1HTR1A | |
| SCHEMBL27334031 | 0.78 | SIGMAR1 (0.56) | EBPSIGMAR1TMEM97ALDH1A1HTR1A | |
| SCHEMBL9028851 | 0.77 | ADRA1D (0.55) | EBPSIGMAR1TMEM97ALDH1A1SMN1; SMN2 | |
| SCHEMBL8828288 | 0.76 | SIGMAR1 (0.54) | EBPSIGMAR1TMEM97HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700385-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027967-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1994-12-08 | — | — | WO | disclosed |