SCHEMBL902799 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MAP4K1	Q92918	2/20	0.49

▸	DGAT1	O75907	8/20	0.43

▸	CDK9	P50750	2/20	0.35

▸	KCNH2	Q12809	4/20	0.35

▸	GSK3B	P49841	1/20	0.35

▸	DYRK1A	Q13627	1/20	0.35

▸	CYP11B1	P15538	3/20	0.35

▸	CYP11B2	P19099	3/20	0.35

▸	FASN	P49327	4/20	0.34

▸	ADORA2A	P29274	1/20	0.34

▸	CCNT1	O60563	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL902595	0.86	DGAT1 (0.61)	MAP4K1DGAT1KCNH2ADORA2A
SCHEMBL902783	0.75	DGAT1 (0.45)	MAP4K1DGAT1KCNH2FASNADORA2A
SCHEMBL902660	0.74	DGAT1 (0.44)	DGAT1KCNH2GSK3BADORA2A
SCHEMBL902778	0.66	DGAT1 (0.64)	DGAT1KCNH2ADORA2A
SCHEMBL902755	0.66	DGAT1 (0.70)	DGAT1KCNH2ADORA2A
SCHEMBL901853	0.66	DGAT1 (0.70)	DGAT1KCNH2ADORA2A
SCHEMBL31289497	0.66	MEN1 (0.52)	—
SCHEMBL902489	0.66	ATR (0.47)	DGAT1
SCHEMBL10189107	0.66	DGAT1 (0.86)	DGAT1KCNH2ADORA2A
SCHEMBL902382	0.66	DGAT1 (0.72)	DGAT1KCNH2ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012044567-A2	IMIDAZOLE DERIVATIVES	MERCK SHARP & DOHME CORP. (US)	2012-04-05	—	—	WO	disclosed