Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902660 | 0.79 | DGAT1 (0.44) | DGAT1KCNH2ADORA2ACLK4SOAT1 | |
| SCHEMBL902799 | 0.75 | MAP4K1 (0.49) | DGAT1KCNH2ADORA2AFASNMAP4K1 | |
| SCHEMBL901744 | 0.73 | DGAT1 (0.58) | DGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL31289497 | 0.70 | MEN1 (0.52) | — | |
| SCHEMBL902489 | 0.70 | ATR (0.47) | DGAT1 | |
| SCHEMBL902382 | 0.70 | DGAT1 (0.72) | DGAT1KCNH2ADORA2ASOAT1 | |
| SCHEMBL10189573 | 0.69 | DGAT1 (0.55) | DGAT1FTOSOAT1 | |
| SCHEMBL15245085 | 0.69 | NPC1 (0.50) | FTO | |
| SCHEMBL31289470 | 0.69 | MEN1 (0.54) | DGAT1SOAT1 | |
| SCHEMBL902206 | 0.69 | DGAT1 (0.61) | DGAT1KCNH2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |