SCHEMBL9028024

SCHEMBL9028024

C=CC=C(C(=O)O)N1CCCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
BLM P54132 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
ALDH1A1 P00352 3/20 0.33
RAB9A P51151 1/20 0.33
STAT6 P42226 1/20 0.33
TP53 P04637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
CASP6 P55212 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7619629 0.81 LMNA (0.41) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL3378771 0.80 LMNA (0.50) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL3378778 0.80 LMNA (0.50) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL3378768 0.80 LMNA (0.50) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL4607217 0.79 LMNA (0.46) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL1737650 0.79 LMNA (0.48) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL28129585 0.79 LMNA (0.48) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL1737652 0.79 LMNA (0.48) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL18402291 0.75 LMNA (0.48) LMNAKMT2AMAPTBLMCYP1A2
SCHEMBL27873089 0.75 LMNA (0.48) LMNAKMT2AMAPTBLMCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2834207-B1 ADJUVANT FOR HYDRAULIC COMPOSITIONS CHRYSO SAS (FR) 2019-05-01 EP disclosed
EP-2834207-A1 ADJUVANT FOR HYDRAULIC COMPOSITIONS Chryso S.A.S. (FR) 2015-02-11 EP disclosed
WO-2013150145-A1 ADJUVANT FOR HYDRAULIC COMPOSITIONS CHRYSO (FR) 2013-10-10 WO disclosed
EP-0504066-B1 Cosmetic compositions containing a dispersion of solid particles surface-coated with a cationic polymer OREAL (FR) 1996-09-04 EP disclosed
EP-0477053-B1 Cosmetic hair composition containing a film-forming polymer and a silicon incorporated in a microdispersion of wax, and its process for cosmetic treatment OREAL (FR) 1994-01-12 EP disclosed
WO-1992016190-A1 COSMETIC COMPOSITIONS CONTAINING A DISPERSION OF SOLID PARTICLES , THE SURFACE OF WHICH IS COATED WITH A CATIONIC POLYMER L'OREAL (FR) 1992-10-01 WO disclosed
EP-0504066-A1 Cosmetic compositions containing a dispersion of solid particles surface-coated with a cationic polymer L'OREAL (FR) 1992-09-16 EP disclosed
EP-0477053-A1 Cosmetic hair composition containing a film-forming polymer and a silicon incorporated in a microdispersion of wax, and its process for cosmetic treatment L'OREAL (FR) 1992-03-25 EP disclosed
US-4645663-A Process for preparing a hair dye or hair bleach composition; a composition for use in this process; and the use of said composition to dye or bleach hair SOCIETE ANONYME DITE: L'OREAL (FR) 1987-02-24 US disclosed
US-4555246-A Process for preparing a hair dye or hair bleach composition; a composition for use in this process; and the use of said composition to dye or bleach hair L'OREAL (FR) 1985-11-26 US disclosed
US-4438095-A New cosmetic compositions for hair or skin conditioning, and the application thereof SOCIETE ANONYME DITE: L'OREAL (FR) 1984-03-20 US disclosed