Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310196 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9027990 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9028887 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9452813 | 0.71 | MEN1 (0.61) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9307946 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9309115 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9028587 | 0.68 | KDM4E (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6774183 | 0.66 | MEN1 (0.62) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL28298203 | 0.65 | CHRM2 (0.79) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL11401365 | 0.65 | ALDH1A1 (0.63) | ALDH1A1KDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486386-B1 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR (FR) | 1996-07-17 | — | — | EP | claimed |
| EP-0486386-A2 | Novel derivatives of N-benzoylproline, process for their preparation and drugs containing them | ADIR ET COMPAGNIE (FR) | 1992-05-20 | — | — | EP | claimed |