Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027275 | 0.88 | HRH3 (0.67) | HRH3CHRNA7HSD17B10KDM4EHRH4 | |
| SCHEMBL9027604 | 0.81 | HRH3 (0.48) | HRH3CHRNA7HRH4DRD2DRD3 | |
| SCHEMBL9027107 | 0.78 | HRH3 (0.66) | HRH3CHRNA7HSD17B10KDM4EHRH4 | |
| SCHEMBL9026162 | 0.76 | HRH3 (0.63) | HRH3CHRNA7HSD17B10KDM4EHRH4 | |
| SCHEMBL9026529 | 0.76 | HRH3 (0.59) | HRH3CHRNA7HSD17B10KDM4EHRH4 | |
| SCHEMBL9026144 | 0.75 | HRH3 (0.46) | HRH3CHRNA7ALDH1A1HRH4 | |
| SCHEMBL31061131 | 0.71 | HRH3 (1.00) | HRH3CHRNA7HSD17B10KDM4EHRH4 | |
| SCHEMBL9028305 | 0.71 | HRH3 (0.53) | HRH3CHRNA7ALDH1A1HSD17B10KDM4E | |
| SCHEMBL27759801 | 0.70 | ALDH1A1 (0.43) | HRH3CHRNA7ALDH1A1HSD17B10KDM4E | |
| SCHEMBL10508496 | 0.70 | HRH3 (0.97) | HRH3CHRNA7HSD17B10KDM4EHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5380723-A | Antiulcer | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |