Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027181 | 0.87 | KDM4E (0.43) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9027275 | 0.83 | HRH3 (0.67) | HRH3DRD2DRD3HRH4CHRNA7 | |
| SCHEMBL9028313 | 0.81 | HRH3 (0.54) | HRH3DRD2DRD3HRH4CHRNA7 | |
| SCHEMBL9026144 | 0.79 | HRH3 (0.46) | HRH3HRH4CHRNA7 | |
| SCHEMBL8681907 | 0.77 | DRD2 (0.68) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9027596 | 0.73 | DRD2 (0.48) | HRH3DRD2DRD3HTR1AHTR7 | |
| SCHEMBL9027107 | 0.73 | HRH3 (0.66) | HRH3DRD2DRD3HRH4CHRNA7 | |
| SCHEMBL9026162 | 0.71 | HRH3 (0.63) | HRH3DRD2DRD3HRH4CHRNA7 | |
| SCHEMBL9026529 | 0.71 | HRH3 (0.59) | HRH3DRD2DRD3HTR7HRH4 | |
| SCHEMBL8681473 | 0.70 | HRH4 (0.68) | HRH3DRD2DRD3HRH4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537532-B1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO (JP) | 1996-11-27 | — | — | EP | disclosed |
| US-5380723-A | Antiulcer | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5326879-A | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0537532-A1 | 2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |