Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | IL2RA | P01589 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416611 | 0.86 | ITGB3 (0.43) | ITGB3ITGA2BF2RIL2RAALB | |
| SCHEMBL7416622 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BF2RIL2RAALB | |
| SCHEMBL9034310 | 0.78 | ALDH1A1 (0.42) | IL2RAALBIL2F2 | |
| SCHEMBL7417270 | 0.77 | ITGB3 (0.45) | ITGB3ITGA2BIL2RAALBIL2 | |
| SCHEMBL7416994 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL7416997 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL7416989 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL9028890 | 0.73 | IL2RA (0.36) | ITGB3ITGA2BIL2RAALBIL2 | |
| SCHEMBL7422078 | 0.73 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL7418292 | 0.73 | ITGB3 (0.55) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |