Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2RA | P01589 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034310 | 0.91 | ALDH1A1 (0.42) | IL2RAALBIL2ALDH1A1HSD17B10 | |
| SCHEMBL7412383 | 0.77 | F10 (0.46) | IL2RAALBIL2ALDH1A1HSD17B10 | |
| SCHEMBL9028509 | 0.73 | ITGB3 (0.43) | IL2RAALBIL2AVPR2AVPR1A | |
| SCHEMBL9028542 | 0.71 | ITGB3 (0.45) | ALDH1A1HSD17B10ITGB3ITGA2BYAP1 | |
| SCHEMBL8140283 | 0.71 | F9 (0.38) | ITGB3ITGA2B | |
| SCHEMBL27352808 | 0.71 | F9 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9034441 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HSD17B10ITGB1ITGA5YAP1 | |
| SCHEMBL7424212 | 0.68 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL7423343 | 0.68 | ITGB3 (0.42) | ITGB3ITGA2B | |
| SCHEMBL7420888 | 0.68 | TP53 (0.45) | IL2RAALBIL2ALDH1A1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-01-17 | — | — | EP | claimed |