Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028582 | 0.89 | SCN9A (0.40) | SCN9ACNR2TYK2LPAR1ROCK2 | |
| SCHEMBL9028568 | 0.86 | SCN9A (0.37) | SCN9ACNR2KDM4ETYK2ADAMTS5 | |
| SCHEMBL9028891 | 0.85 | LIMK1 (0.37) | SCN9ACNR2KDM4ETYK2ADAMTS5 | |
| SCHEMBL9028689 | 0.84 | SCN9A (0.37) | SCN9ACNR2TYK2ROCK2TNF | |
| SCHEMBL9030025 | 0.83 | GPBAR1 (0.38) | SCN9ATYK2 | |
| SCHEMBL9028966 | 0.82 | HPGD (0.36) | SMN1; SMN2SCN9ACNR2TYK2ADAMTS5 | |
| SCHEMBL8550618 | 0.79 | LIPE (0.43) | KDM4E | |
| SCHEMBL8549639 | 0.79 | GPBAR1 (0.37) | SCN9ACNR2 | |
| SCHEMBL27437030 | 0.77 | LIPE (0.33) | SCN9ATYK2ADAMTS5CTSA | |
| SCHEMBL9028163 | 0.76 | AKR1C3 (0.41) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |