Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HA1 | P13674 | 2/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 13/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902702 | 0.70 | DGAT1 (0.47) | DGAT1 | |
| SCHEMBL10188659 | 0.65 | DGAT1 (0.56) | DGAT1LDHA | |
| SCHEMBL14822500 | 0.65 | P4HA1 (0.59) | P4HA1P4HTMLDHAHCAR3 | |
| SCHEMBL30590918 | 0.65 | P4HA1 (0.59) | P4HA1P4HTMLDHAHCAR3 | |
| SCHEMBL29683317 | 0.64 | P4HTM (1.00) | P4HA1P4HTMLDHAHCAR3 | |
| SCHEMBL29397057 | 0.64 | P4HTM (1.00) | P4HA1P4HTMLDHAHCAR3 | |
| SCHEMBL68560 | 0.64 | P4HTM (1.00) | P4HA1P4HTMLDHAHCAR3 | |
| SCHEMBL16749631 | 0.63 | P4HA1 (0.79) | P4HA1P4HTMLDHAHCAR3 | |
| Potassium SCHEMBL30900922 | 0.62 | P4HTM (0.95) | P4HA1P4HTMLDHAHCAR3 | |
| Hydrochloric Acid SCHEMBL8871610 | 0.62 | P4HTM (0.95) | P4HA1P4HTMLDHAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044567-A2 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |